Dynamics of clinical and functional parameters of periodontal tissues in the treatment of plaque-induced gingivitis in children with type 1 diabetes mellitus

Relevance. One of the key features of periodontal health status in children with type 1 diabetes mellitus is the high prevalence of inflammatory periodontal diseases. Additionally, diabetes-associated microangiopathies can contribute to various complications, including those affecting oral tissues

Materials and methods. The study included three groups of patients aged 6 to 17 years. The first (n = 20) and second (n = 19) groups comprised children with a history of type 1 diabetes mellitus and clinical signs of periodontal inflammation. The third group (n = 20) consisted of systemically healthy children. All participants underwent professional oral prophylaxis. In addition to conventional periodontal therapy, the first group received an adjunctive agent Superlimf containing a complex of cytokines and antimicrobial peptides. Treatment efficacy was assessed based on clinical parameters and functional evaluation of periodontal tissue hemodynamics before treatment and one month post-therapy.

Results. Treatment of plaque-induced gingivitis in children with type 1 diabetes mellitus led to improvements in clinical parameters, with more pronounced changes observed in the first group. Functional assessment of periodontal status also showed positive changes in microcirculation and oxygenation of periodontal tissues.

Conclusion. The adjunctive use of a cytokine- and antimicrobial peptide-based agent demonstrated significant clinical and functional efficacy in reducing inflammatory processes in periodontal tissues in children with type 1 diabetes mellitus. These findings support the inclusion of such agents in the comprehensive management of inflammatory periodontal diseases.’

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