Clinical and laboratory analysis of the effectiveness of caries-preventive gel applications in active carious lesions in children

Relevance. Tooth decay and its complications are the most common diseases worldwide. Prevention is the most effective way to fight the disease. It is reasonable to develop scientific research connected with a complex advanced analysis of metabolic processes in the oral cavity associated with fluoride-free caries-preventive product use in a pediatric dental clinic and their possible combination with fluoride-containing products.

Purpose. The study aimed to conduct a comparative clinical and laboratory analysis of the effectiveness of cariespreventive gel compositions in mixed dentition with active carious lesions to specify practical recommendations.

Materials and methods. We examined 1989 schoolchildren aged 7 to 12 years old. The patients with active carious lesions (60 people) formed two subgroups for more detailed research. We treated and taught oral hygiene children of both groups. The first group (comparison group) was recommended brushing their teeth with a fluoride toothpaste containing 1450 ppm fluoride. The second group (main group) used the authors' calcium-phosphate remineralizing gel (subgroup 1), developed at the Department of Pediatric Dentistry (Omsk State Medical University) or a commercially available calcium glycerophosphate remineralizing gel (subgroup 2).

Results. On prevention and treatment, clinical indices of the oral organ and tissue condition statistically significantly improved in all observation groups. The evidence again confirmed that oral hygiene improvement leads to a marginal gum inflammation decrease and reduces the risk of future periodontal diseases as the child grows up. Conclusion. Changing the standard prevention scheme, prolonging the use of a remineralizing gel, prescribing professional topical fluoride-containing products and recommending vitamin-mineral, fluoride and calcium supplements to take orally upon consultation with a pediatrician are presumably reasonable for more successful prevention in active carious lesions.

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