Efficacy and safety of calcium glycerophosphate-based toothpastes in children

Relevance. The effectiveness of toothpastes has been proven by numerous studies. Toothpaste - a multi-system, the effectiveness of which should be commensurate with its safety. Purpose. To determine the effectiveness and safety of toothpastes based on calcium glycerophosphate. Materials and methods. 136 children and adolescents aged 7-15 years were examined. All children were divided into groups depending on the toothpaste they used for oral hygiene 2 times a day. The principle of division into groups was based on the choice of parents and children. The first group consisted of children (46 people) who used toothpaste R. O. C. S. "Active Calcium". The second group consisted of patients (44 persons) using toothpaste R. O. C. S. PRO "Young & White Enamel". The third group included children (46 people) using any other toothpaste that does not contain calcium glycerophosphate. Determined index hygiene O’Leary, the speed of salivation, the viscosity of the saliva, buffering capacity of saliva. The influence of toothpastes on the body sensitization was determined by CAST-test. Results. After three months in children of study groups the hygiene index improved significantly, the rate of salivation increased and the viscosity of saliva decreased. In the control group these indicators have not changed significantly. The coefficient of activated basophils of blood serum in the first two groups of the study had no significant differences and was on average 1.040 ± 0.009 for the first group and 1.05 ± 0.02 for the second group. A similar indicator in children of the control group was 1.15 ± 0.03, which exceeds the reference values and can be a marker of the sensitizing effect of toothpastes on the body. Conclusions. It is established that toothpastes based on calcium glycerophosphate effectively remove plaque, stabilize the cariesogenic situation in the oral cavity and do not have a sensitizing effect on the body of children.

зубной налет, зубная паста, глицерофосфат кальция, сенсибилизация, plaque, toothpaste, calcium glycerophosphate, sensitization