Clinical study on the efficacy of a whitening toothpaste and mouthwash
https://doi.org/10.33925/1683-3031-2025-934
Abstract
Relevance. This study presents the results of a clinical evaluation of a whitening toothpaste and mouthwash used together to prevent dental plaque formation. The products demonstrated effective cleaning, a pronounced refreshing and whitening effect, cumulative improvement in oral hygiene, reduction of inflammation, anticaries activity, and decreased tooth sensitivity.
Objective. To evaluate, in a clinical setting, the efficacy of a whitening toothpaste and mouthwash combination.
Materials and methods. The efficacy of the toothpaste and mouthwash in preventing plaque formation was assessed using the Green–Vermillion Hygiene Index, Interdental Hygiene Index, PMA and SBI periodontal indices, enamel resistance, enamel hypersensitivity, tooth color and whitening effect, and refreshing effect measured with a visual analogue scale (VAS).
Results. Oral hygiene indices demonstrated significant advantages of the tested products, including high cleaning efficacy, a pronounced refreshing effect, and cumulative improvement in oral hygiene. The cleaning and deodorizing effects were more pronounced when the toothpaste and mouthwash were used together. The products significantly reduced oral inflammation and gingival bleeding, increased enamel acid resistance (indicating enhanced caries prevention), and decreased tooth sensitivity while producing a visible whitening effect.
Conclusion. Combined use of the toothpaste and mouthwash increased enamel acid resistance, which supports effective caries prevention. It also reduced tooth sensitivity and enhanced the whitening effect. Both products were well tolerated and caused no allergic reactions or irritation.
Keywords
About the Authors
S. I. TokmakovaRussian Federation
Svetlana I. Tokmakova, DMD, PhD, DSc, Professor, Head of the Department of Operative Dentistry
Barnaul
O. V. Bondarenko
Russian Federation
Olga V. Bondarenko, DMD, PhD, Associate Professor, Department of Operative Dentistry
Barnaul
E. A. Kirienkova
Russian Federation
Ekaterina A. Kirienkova, DMD, PhD, Associate Professor, Department of Operative Dentistry
40 Lenin prospect, Barnaul, Russian Federation, 656038
N. V. Savitskaya
Russian Federation
Natalia V. Savitskaya, Clinical Research Manager
Moscow
O. E. Shishkina
Russian Federation
Oksana E. Shishkina, DMD, Associate Professor, Department of the Prosthodontics with the course of Oral and Maxillofacial Surgery
Barnaul
A. S. Stuzhuk
Russian Federation
Anna S. Stushuk, DMD, Associate Professor, Department of the Prosthodontics and General Dentistry
Barnaul
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Supplementary files
Review
For citations:
Tokmakova S.I., Bondarenko O.V., Kirienkova E.A., Savitskaya N.V., Shishkina O.E., Stuzhuk A.S. Clinical study on the efficacy of a whitening toothpaste and mouthwash. Pediatric dentistry and dental prophylaxis. 2025;25(3):235-246. (In Russ.) https://doi.org/10.33925/1683-3031-2025-934





























