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Clinical study on the efficacy of a whitening toothpaste and mouthwash

https://doi.org/10.33925/1683-3031-2025-934

Abstract

Relevance. This study presents the results of a clinical evaluation of a whitening toothpaste and mouthwash used together to prevent dental plaque formation. The products demonstrated effective cleaning, a pronounced refreshing and whitening effect, cumulative improvement in oral hygiene, reduction of inflammation, anticaries activity, and decreased tooth sensitivity.

Objective. To evaluate, in a clinical setting, the efficacy of a whitening toothpaste and mouthwash combination.

Materials and methods. The efficacy of the toothpaste and mouthwash in preventing plaque formation was assessed using the Green–Vermillion Hygiene Index, Interdental Hygiene Index, PMA and SBI periodontal indices, enamel resistance, enamel hypersensitivity, tooth color and whitening effect, and refreshing effect measured with a visual analogue scale (VAS).

Results. Oral hygiene indices demonstrated significant advantages of the tested products, including high cleaning efficacy, a pronounced refreshing effect, and cumulative improvement in oral hygiene. The cleaning and deodorizing effects were more pronounced when the toothpaste and mouthwash were used together. The products significantly reduced oral inflammation and gingival bleeding, increased enamel acid resistance (indicating enhanced caries prevention), and decreased tooth sensitivity while producing a visible whitening effect.

Conclusion. Combined use of the toothpaste and mouthwash increased enamel acid resistance, which supports effective caries prevention. It also reduced tooth sensitivity and enhanced the whitening effect. Both products were well tolerated and caused no allergic reactions or irritation.

About the Authors

S. I. Tokmakova
Altai State Medical University
Russian Federation

Svetlana I. Tokmakova, DMD, PhD, DSc, Professor, Head of the Department of Operative Dentistry

Barnaul



O. V. Bondarenko
Altai State Medical University
Russian Federation

Olga V. Bondarenko, DMD, PhD, Associate Professor, Department of Operative Dentistry

Barnaul



E. A. Kirienkova
Altai State Medical University
Russian Federation

Ekaterina A. Kirienkova, DMD, PhD, Associate Professor, Department of Operative Dentistry

40 Lenin prospect, Barnaul, Russian Federation, 656038



N. V. Savitskaya
Moscow branch office of SkyLab AG
Russian Federation

Natalia V. Savitskaya, Clinical Research Manager

Moscow



O. E. Shishkina
Altai State Medical University
Russian Federation

Oksana E. Shishkina, DMD, Associate Professor, Department of the Prosthodontics with the course of Oral and Maxillofacial Surgery

Barnaul



A. S. Stuzhuk
Altai State Medical University
Russian Federation

Anna S. Stushuk, DMD, Associate Professor, Department of the Prosthodontics and General Dentistry

Barnaul



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Supplementary files

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For citations:


Tokmakova S.I., Bondarenko O.V., Kirienkova E.A., Savitskaya N.V., Shishkina O.E., Stuzhuk A.S. Clinical study on the efficacy of a whitening toothpaste and mouthwash. Pediatric dentistry and dental prophylaxis. 2025;25(3):235-246. (In Russ.) https://doi.org/10.33925/1683-3031-2025-934

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ISSN 1683-3031 (Print)
ISSN 1726-7218 (Online)