Systematic review of current approaches to comprehensive management of children with unilateral mandibular ramus hypoplasia or aplasia in congenital osseous disorders of the temporomandibular joint. Part II: Orthodontic management
https://doi.org/10.33925/1683-3031-2025-904
Abstract
Relevance. Orthodontic management of children with congenital osseous disorders of the temporomandibular joint (TMJ) spans the entire course of dentofacial growth and accompanies each surgical stage from early childhood through adolescence. Although a wide range of orthodontic appliances is available for this patient group, published data on their use remain limited and inconsistent. Evidence from Russian and international sources suggests that combining functional orthopedic treatment with distraction osteogenesis (DO) yields more durable, clinically stable outcomes. However, the sequence of appliance use and continuity of care remain poorly organized and insufficiently systematized, a gap compounded by the absence of a unified clinical algorithm and formal practice guidelines. Objective. To analyze existing orthodontic management methods for patients with mandibular ramus hypoplasia and/or aplasia across the stages of comprehensive rehabilitation and to synthesize the available evidence.
Materials and methods. The literature review was conducted in accordance with PRISMA guidelines for systematic reviews and meta-analyses. Searches were performed in PubMed, Medline, EMBASE, and eLibrary using the keywords “orthodontic management,” “mandibular ramus hypoplasia and aplasia,” “functional appliance,” and “stages of orthodontic treatment,” combined with the Boolean operator AND, in both English and Russian. Original publications reporting the use of removable orthodontic appliances in patients with congenital osseous TMJ disorders were analyzed. A total of 1,500 records were identified; 22 met the inclusion criteria and were included in the final review. In addition, a retrospective analysis was conducted of orthodontic outcomes in 40 patients treated at the Department of Orthodontics, A.I. Yevdokimov Moscow State University of Medicine and Dentistry, from 2004 to 2024.
Results. Reports in the Russian-language literature describing specific functional orthodontic appliances for children with unilateral mandibular ramus hypoplasia and/or aplasia due to congenital osseous TMJ disorders are scarce. Most published cases involve the Vankevich appliance (maxilla-supported fracture splint) or a removable plate with a lingual pad (pelotte). To date, no standardized protocol for orthodontic management of these patients has been proposed.
Conclusion. In this patient population, criteria for evaluating the quality of orthodontic care across stages of dentofacial development are lacking, and the continuity of multidisciplinary collaboration within comprehensive dental rehabilitation is insufficiently characterized. A clear clinical strategy for orthodontic management has not been defined, and the biomechanical capabilities of orthodontic appliances in influencing both jaws both jaws are not fully delineated. The optimal integration of surgical and orthodontic stages into a unified, evidence-based treatment protocol also remains to be established.
About the Authors
E. A. ChepikRussian Federation
Ekaterina A. Chepik, DMD, PhD, Assistant Professor, Department of the Orhtodontics
4 Dolgorukovskaya Str., Moscow, 127006
O. Z. Topolnitsry
Russian Federation
Orest Z. Topolnitsky, DDS, PhD, DSc, Professor, Honored Doctor of the Russian Federation Head of the Pediatric Maxillofacial Surgery
Moscow
L. G. Tolstunov
Russian Federation
Leonid G. Tolstunov, DMD, PhD, Associate Professor, Department of the Dentistry
Moscow
References
1. Imshenetskaya N.I., Topol'nitskiy O.Z., Lezhnev D.A., Gioeva Yu.A., Yanushevich S.O., Chepik E.A. Examination and treatment of patients with aplasia of mandibular branch in craniofacial microsomy using a multidisciplinary approach. Ortodontiya. 2023;(3):39-45 (In Russ.). Available from: https://elibrary.ru/item.asp?id=60024596
2. Korsak A.K. Treatment of children with ankylosis of the temporomandibular joint. Sovremennaya stomatologiya. 2005;(4):50-54 (In Russ.). Available from: https://www.mednovosti.by/journal.aspx?article=3137
3. Seregin A.S., Postnikov M.A., Vorozhejkina N.A., Ustina M.V., Slesarev O.V., Kolyvanov A.A., Karpov A.N., inventors. Center of Complex Dentistry LLC, assignee. Method of rehabilitation of children with anchylosis of temporomandibular joint and mandibular contractures in postoperative period. Russian Federation patent RU 2674116 C1. 2018 December 4 (In Russ.). Available from: https://elibrary.ru/item.asp?id=37363655
4. Starikova N.V., Babaev J.A., Kharchenko M.N., Cherevko Ya.S., Smironova O.V., Berntaov Y.M., inventors. Babaev D.Ya., assignee. A double-jaw device for verticalization and elimination of mandibular deflection. Russian Federation patent. RU 217292 U1. 2023 March 27 (In Russ.). Available from: https://elibrary.ru/item.asp?id=50434230
5. Starikova N.V., Babaev J.A., Kharchenko M.N., Cherevko Ya.S., Smironova O.V., Berntaov Y.M., inventors. Babaev DYa, assignee. A device for verticalization of the mandible and elimination of deflection. Russian Federation patent. RU RU 218404 U1. 2023 May 25. (In Russ.). Available from: https://elibrary.ru/item.asp?id=54057007
6. Slabkovskaia A.B. Principles of treatment for children with transversal abnormalities of occlusion. Russian Journal of Stomatology. 2010;3(1):40-44 (In Russ.). Available from: https://elibrary.ru/item.asp?id=23341238
7. Cassi D, Magnifico M, Di Blasio C, Gandolfini M, Di Blasio A. Functional Treatment of a Child with Extracapsular Mandibular Fracture. Case Rep Dent. 2017;2017:9760789. https://doi.org/10.1155/2017/9760789
8. Cassi D, Magnifico M, Gandolfinini M, Kasa I, Mauro G, Di Blasio A. Early Orthopaedic Treatment of Hemifacial Microsomia. Case Rep Dent. 2017;2017:7318715. https://doi.org/10.1155/2017/7318715
9. Cozza P, Baccetti T, Franchi L, De Toffol L, McNamara JA Jr. Mandibular changes produced by functional appliances in Class II malocclusion: a systematic review. Am J Orthod Dentofacial Orthop. 2006;129(5):599.e1-12; discussion e1-6. https://doi.org/10.1016/j.ajodo.2005.11.010
10. Di Blasio C, Di Blasio A, Pedrazzi G, Anghinoni M, Sesenna E. How does the mandible grow after early high condylectomy. J Craniofac Surg. 2015;26(3):764-71. https://doi.org/10.1097/SCS.0000000000001515
11. El-Bialy T, Hasan A, Janadas A, Albaghdadi T. Nonsurgical treatment of hemifacial macrosomia by therapeutic ultrasound and hybrid functional appliance. Open Access J Clin. Trials. 2010; 2: 29-39. https://doi.org/10.2147/OAJCT.S7060
12. Lauritzen C, Munro IR, Ross RB. Classification and treatment of hemifacial microsomia. Scand J Plast Reconstr Surg. 1985;19(1):33-39. https://doi.org/10.3109/02844318509052863
13. Leonardi R, Barbato E. Mandibular asymmetry treated with a modified activator appliance. J Craniofac Surg. 2007;18(4):939-43. https://doi.org/10.1097/scs.0b013e3180a77206
14. Liu CK, Meng FW, Tan XY, Xu J, Liu HW, Liu SX, et al. Clinical and radiological outcomes after treatment of sagittal fracture of mandibular condyle (SFMC) by using occlusal splint in children. Br J Oral Maxillofac Surg. 2014;Feb;52(2):144-8. https://doi.org/10.1016/j.bjoms.2013.10.007
15. Ongkosuwito EM, van Vooren J, van Neck JW, Wattel E, Wolvius EB, van Adrichem LN, Kuijpers-Jagtman AM. Changes of mandibular ramal height, during growth in unilateral hemifacial microsomia patients and unaffected controls. J Craniomaxillofac Surg. 2013;41(2):92-97. https://doi.org/10.1016/j.jcms.2012.05.006
16. Proffit WR, Vig KW, Turvey TA. Early fracture of the mandibular condyles: frequently an unsuspected cause of growth disturbances. Am J Orthod. 1980;78(1):1-24. https://doi.org/10.1016/0002-9416(80)90037-8
17. Rune B, Sarnäs KV, Selvik G, Jacobsson S. Roentgen stereometry with the aid of metallic implants in hemifacial microsomia. Am J Orthod. 1983;84(3):231-47. https://doi.org/10.1016/0002-9416(83)90131-8
18. Silvestri A, Natali G, Iannetti G. Functional therapy in hemifacial microsomia: therapeutic protocol for growing children. J Oral Maxillofac Surg. 1996;54(3):271-8; discussion 278-80. https://doi.org/10.1016/s0278-2391(96)90738-7
19. Vargervik K, Miller AJ. Neuromuscular patterns in hemifacial microsomia. Am J Orthod. 1984;86(1):33-42. https://doi.org/10.1016/0002-9416(84)90274-4
20. Wang J, Yuan L, Liu J, Mao L, Xia L, Fang B. Hemifacial microsomia treated with a hybrid technique combining distraction osteogenesis and a mandible-guided functional appliance: Pilot study. Am J Orthod Dentofacial Orthop. 2019;155(6):801-811. https://doi.org/10.1016/j.ajodo.2018.06.020
21. Zanardi G, Parente EV, Esteves LS, Louro RS, Capelli J Jr. Orthodontic and surgical treatment of a patient with hemifacial microsomia. Am J Orthod Dentofacial Orthop. 2012;141(4 Suppl): S130-9. https://doi.org/10.1016/j.ajodo.2011.02.028
22. Zhao YM, Yang J, Bai RC, Ge LH, Zhang Y. A retrospective study of using removable occlusal splint in the treatment of condylar fracture in children. J Craniomaxillofac Surg. 2014;42(7):1078-82. https://doi.org/10.1016/j.jcms.2012.07.010
Review
For citations:
Chepik E.A., Topolnitsry O.Z., Tolstunov L.G. Systematic review of current approaches to comprehensive management of children with unilateral mandibular ramus hypoplasia or aplasia in congenital osseous disorders of the temporomandibular joint. Part II: Orthodontic management. Pediatric dentistry and dental prophylaxis. 2025;25(2). (In Russ.) https://doi.org/10.33925/1683-3031-2025-904





























