Characteristics of inflammatory disease structure in the maxillofacial region among children of different age groups in Krasnodar Krai

Relevance. Acute purulent-inflammatory diseases of the maxillofacial region (APID-MFR) are the leading cause of pediatric referrals to the maxillofacial surgery department. The prevalence of APID-MFR requiring hospitalization among children in Krasnodar and Krasnodar Krai averaged 42.9% from 2017 to 2021.

Objective. To investigate the nature and structure of odontogenic and non-odontogenic inflammatory processes in patients treated at the maxillofacial surgery department of the State Healthcare Institution "Children’s Regional Clinical Hospital" (CRCH), Krasnodar.

Materials and methods. Medical records of patients with inflammatory diseases of the maxillofacial region, treated in the maxillofacial surgery department at CRCH, Krasnodar, from 2017 to 2021, were analyzed. The study focused on examining the structure and characteristics of the pathology in patients receiving inpatient care.

Results. The most common pathology identified in children was periostitis (30.9%), which significantly differed (p = 0.007) from the second most prevalent condition, exacerbation of chronic periodontitis (26.1%). The third place was shared by lymphadenitis (13.6%) and inflammatory skin and subcutaneous tissue diseases, including boils and carbuncles (13.5%), both of which significantly differed from the top two conditions (p < 0.001) but not from each other (p > 0.05). In fourth, fifth, and sixth places were other inflammatory skin and subcutaneous tissue diseases: abscess (10.1%), phlegmon (4.8%), and adenophlegmon (1.0%), which also significantly differed from one another.

Conclusion. The high prevalence of odontogenic APID-MFR in children highlights the insufficient prevention of caries-related complications and emphasizes the need for enhanced pediatric dental care. Early diagnosis and prevention of APID-MFR complications are crucial to improving outcomes in affected children.

1. Zhelezny PA, Kolybelkin MV, Izyumov AO, Apraksina EYu, Zheleznaya AP, Shchelkunov KS, et al. Structure and nature of inflammatory processes of the maximumfacial region IN children. Medical science and education of Urals. 2017;2(90):91-94 (In Russ.). Available from: https://www.elibrary.ru/download/elibrary_29371760_83991219.pdf

2. Zheleznyi PA, Kolybelkin MV, Izyumov AO, Apraksina EYu, Zheleznaya AP. Features of odontogenic and nonodontogenic inflammatory maxillofacial processes in children undergone treatment in the maxillofacial inpatient department. Journal of Siberian Medical Sciences. 2018;(3):31-39 (In Russ.). Available from: https://elibrary.ru/item.asp?id=35119225

3. Kabanova S, Kabanova A, Fleryanovitch M, Goncharova A. Antibacterial therapy for patients with infectious diseases of the maxillofacial region at various stages of treatment. Sovremennaya stomatologiya. 2022; 3 (88): 22-26. (In Russ.) Available from: https://www.elibrary.ru/item.asp?id=49750242

4. Mitropanova MN, Ponomarenko TA, Chudilova GA, Teterin YuV, Chapurina VN. Immune system dysfunction in purulent inflammatory diseases of the maxillofacial area in pediatric patient. Russian Journal of Immunology. 2023;26(4):579-586 (In Russ.). doi: 10.46235/1028-7221-13992-ISD

5. Mitropanova MN, Ponomarenko TA, Lyubomirskaya EO, Frolkina EN, Antoniadis SS, Zobenko VYa. Analysis of the prevalence of inflammatory diseases of the maxillofacial region in children of the Krasnodar territory. Clinical dentistry (Russia). 2023;26(2):93-97 (In Russ.). doi: 10.37988/1811-153X_2023_2_93

6. Almeida de AS, Kato CNO, Jácome-Santos H, Pinheiro JJ, Mesquita RA, Abreu LG. A retrospective analysis of oral and maxillofacial lesions in children and adolescents reported in two different services. J Clin Exp Dent. 2021;13(9):e894-e905. doi: 10.4317/jced.58231

7. Huang G, Moore L, Logan RM, Gue S. Retrospective analysis of South Australian pediatric oral and maxillofacial pathology over a 16-year period. J Investig Clin Dent. 2019;10(3):e12410. doi: 10.1111/jicd.12410

8. Izyumov AO, Noskova EV, Kolybelkin MV, Apraksina EY, Borodina TV, Klimova IV, et al. Inflammatory diseases of maxillofacial area at children. Medicina i obrazovanie v Sibiri. 2015;(5):43 (In Russ.). Available from: https://elibrary.ru/item.asp?id=25124940

9. Parshikova SA, Glyavina IA, Kosyuga SYu, Slesareva OA. Clinical and statistical analysis of traumatic injuries and inflammatory diseases of the maxillofacial region (based on the work of the Department of maxillofacial surgery department of Nizhny Novgorod Regional Children's Clinical Hospital from 2013 to 2017). Modern problems of science and education. 2018;(5):89 (In Russ.). Available from: https://science-education.ru/ru/article/view?id=28136

10. Kiselnikova LP, Tsarev VN, Toma EI, Podporin MS. Microbiocenosis of the oral cavity of children: clinical and microbiological characteristics and correction with probiotics based on salivary streptococci. Clinical Dentistry (Russia). 2021;24(4):24-29 (In Russ.). doi: 10.37988/1811-153X_2021_4_24

11. Kruzhilin VV, Chechina IN, Zhilenko OG, Podzorova EA, Sarap LR, Dmitrienko NYu. Caries activity dependence on the oral ion balance in children. Clinical Dentistry (Russia). 2022;25(4):14-19. doi: 10.37988/1811-153X_2022_4_14

12. Mustafajev MS, Kharaeva ZF, Zhanataeva ML. Interendolysin status of children with purulent and inflammatory diseases of the maxillofacial region. Fundamental research. 2013;7-3:594-597 (In Russ.). Available from: https://elibrary.ru/item.asp?id=19693299

13. Yu Z, Seo B, Hussaini HM, Meldrum AM, Rich AM. The relative frequency of paediatric oral and maxillofacial pathology in New Zealand: A 10-year review of a national specialist centre. Int J Paediatr Dent. 2020;30(2):209-215. doi: 10.1111/ipd.12590

14. Khalyuta EE, Mokhnacheva SB, Berdichevskaya EV, Nagumanov RA. Features of the course of acute odontogenic inflammatory jaw processes in childhood. Journal of Volgograd State Medical University. 2022;19(4):152-156 (In Russ.). doi: 10.19163/1994-9480-2022-19-4-152-156

15. Anokhina IV, Zabelin AS, Slabkaya EV. Patterns of immune reactivity in children with acute face and neck lymphadenitis. Smolenskij medicinskij al'manah. 2020; (3): 24-28 (In Russ.). Available from: https://elibrary.ru/item.asp?id=44096913

16. Kabanova AA. Indicators of immune status of patients with inflammatory diseases of the maxillofacial area and neck depending from the process severity. Medicine and ecology. 2019;(1):69-76 (In Russ.). Available from: https://medecol.elpub.ru/jour/article/view/98

17. Durnovo EA, Vysel’tseva IuV, Mishina NV, Khomutinnikova NE, Oleneva IuV, Katkova IuO, et al. Clinical immunological peculiarities of complicated course of odontogenic phlegmons of maxillofacial region. Stomatologiya. 2010;89(2):29-31 (In Russ.). Available from: https://www.elibrary.ru/item.asp?id=16599401

18. Porfiriadys MP, Sashkina TI, Shulakov VV, Karakov KG, Birjulov AA. The dynamics of nonspecific immunityindicators in patients with maxillofacial area phlegmons and possibility of its correction. Medical news of North Caucasus. 2010;2:44-45 (In Russ.). Available from: https://elibrary.ru/item.asp?id=15287677