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Effectiveness of Argymax spray in treating xerostomia in pregnant women with isthmic-cervical insufficiency

https://doi.org/10.33925/1683-3031-2024-732

Abstract

Relevance. Xerostomia, commonly known as dry mouth, is a prevalent orofacial disorder among pregnant women experiencing isthmic-cervical insufficiency. This condition manifests as a burning sensation in the mouth, pain, and discomfort during eating. A clear correlation exists between pain, taste alterations, and the perception of oral dryness, highlighting the multifaceted impact of xerostomia on affected individuals. Pregnant women with isthmic-cervical insufficiency, a complication that significantly increases the risk of preterm labor, are particularly susceptible to xerostomia. This condition is often accompanied by heightened psycho-emotional stress, which can exacerbate the symptoms of dry mouth. Despite the multitude of treatments available for xerostomia, the primary objective for dentists is to formulate an appropriate and effective treatment plan, tailored to the physiological needs of the patient. This study evaluates the efficacy of Argymax spray in alleviating xerostomia in pregnant women with isthmic-cervical insufficiency.

Materials and methods. A study was conducted involving 84 pregnant women who were assessed and treated over a three-week period to evaluate the rate of mixed saliva secretion. Subjective data were collected using a five-point scale to analyze the reduction in pain potential, itching, and burning. Hygienic and periodontal indices were determined before therapy and three months after the use of the spray.

Results. The study demonstrated that Argymax spray begins to act within seven days of initial application and maintains its effectiveness throughout the observation period.

Conclusion. Hormonal changes during pregnancy affect both the overall body and the condition of the oral cavity, making it particularly vulnerable. Early diagnosis and appropriate management strategies can prevent the development of several oral mucosal diseases associated with xerostomia. Argymax spray is recommended as symptomatic therapy for the treatment of xerostomia in pregnant women with isthmic-cervical insufficiency.

About the Authors

A. V. Mosyagina
Dental clinic No. 9
Russian Federation

Anastasia V. Mosyagina, DMD, Head of the Department of Operative Dentistry

Volgograd



Yu. A. Makedonova
Volgograd State Medical University; Volgograd Medical Research Center
Russian Federation

Yulia A. Makedonova, DMD, PhD, DSc, Head of the Department of Dentistry, Institute of Continuing Medical and Pharmaceutical Education; Senior Researcher

Volgograd



M. V. Nechaev
PE Nechaev Maxim Viktorovich
Russian Federation

Maxim V. Nechaev, CEO of Argymax company, Private Entrepreneur Nechaev Maxim Viktorovich

Volgograd



E. N. Yarygina
Volgograd State Medical University
Russian Federation

Elena N. Yarygina, DDS, PhD, Head of the Department of Surgical Dentistry and Maxillofacial Surgery

Volgograd



N. I. Sviridova
Volgograd State Medical University
Russian Federation

Natalia I. Sviridova, MD, PhD, DSc, Head of the Department of Obstetrics and Gynecology, Institute of Continuing Medical and Pharmaceutical Education

Volgograd



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For citations:


Mosyagina A.V., Makedonova Yu.A., Nechaev M.V., Yarygina E.N., Sviridova N.I. Effectiveness of Argymax spray in treating xerostomia in pregnant women with isthmic-cervical insufficiency. Pediatric dentistry and dental prophylaxis. 2024;24(2):117-124. (In Russ.) https://doi.org/10.33925/1683-3031-2024-732

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ISSN 1683-3031 (Print)
ISSN 1726-7218 (Online)