Riga-Fede disease: a review of the literature and a description of clinical cases
https://doi.org/10.33925/1683-3031-2023-614
Abstract
Relevance. Riga-Fede disease (RFD) is a rare pathology that develops as a result of trauma to the mucous membrane of the tongue ventral surface with sharp edges of natal, neonatal or primary teeth erupting in time and manifests in the form of erosion or sublingual fibrous lesion with an ulcerated surface.
Purpose. To analyze the literature and present our own RFD clinical cases.
Material and methods. A search was performed of articles published in 2001-2023 on the research topic in the main scientific literature databases (PubMed, E-library, Google Scholar, etc.). We analyzed the data from 68 publications and presented three of our own clinical cases of RFD in children aged 5, 6 and 9 months.
Results. Analysis of literature data revealed different approaches to the diagnosis and treatment of RFD in children. The diagnosis of RFD should rely on the clinical picture and exclude additional trauma to children by histological examination and lesion excision. Pronounced tooth mobility, ineffective infant feeding and the presence of neurological diseases in patients were the main indications for the extraction of teeth, which caused RFD development. In the absence of tooth mobility, non-surgical treatment methods should be preferable. In the presented clinical cases, erupted primary teeth caused BRF. In two cases, the treatment consisted of smoothing the sharp edges of the teeth and restoration with glass ionomer cement; in one case, a child with a neurological disease experienced extraction of lower central incisors. In all cases, recovery was within 3-4 weeks.
Conclusion. Once clinically diagnosed with RFD, treatment method choice should consider tooth mobility and the child's overall health.
About the Authors
I. V. Fomenko
Volgograd State Medical University
Russian Federation
Russian Federation
Irina V. Fomenko, DMD, PhD, DSc, Professor, Head of Department of Paediatric Dentistry
Volgograd
E. E. Maslak
Volgograd State Medical University
Russian Federation
Russian Federation
Elena E. Maslak, DMD, PhD, DSc, Professor, Department of Paediatric Dentistry
Volgograd
A. L. Kasatkina
Volgograd State Medical University
Russian Federation
Russian Federation
Anjella L. Kasatkina, DMD, PhD, Associate Professor, Department of Paediatric Dentistry
Volgograd
V. V. Bavlakova
Volgograd State Medical University
Russian Federation
Russian Federation
Viktoria V. Bavlakova, DMD, PhD, Associate Professor, Department of Orthodontics
Volgograd
D. I. Fursik
Volgograd State Medical University
Russian Federation
Russian Federation
Denis I. Fursik, DMD, PhD, Associate Professor, Department of Pediatric Dentistry
Volgograd
References
1. Ceyhan AM, Yildirim M, Basak PY, Akkaya VB, Ayata A. Traumatic lingual ulcer in a child: Riga-Fede disease. Clin Exp Dermatol. 2009;34(2):186-188. doi: 10.1111/j.1365-2230.2008.02796.x
2. Singhal P, Bhateja S, Vengal M. Riga Fede disease: a case report. Annals Essences Dentistry. 2014;6(1):19-21. doi: 10.5958/0976-156X.2014.00006.9
3. Jariwala D, Graham RM, Lewis T. Riga-Fede disease. Br Dent J. 2008;204(4):171. doi: 10.1038/bdj.2008.113
4. Mathew MG. Riga Fede disease in twins. BMJ Case Rep. 2022;10;15(11):e252226. doi: 10.1136/bcr-2022-252226
5. Zaenglein AL, Chang MW, Meehan SA, Axelrod FB, Orlow SJ: Extensive Riga-Fede disease of the lip and tongue. J Am Acad Dermatol. 2002;47(3):445–447. doi: 10.1067/mjd.2002.117213
6. Campos-Muñoz L, Quesada-Cortés A, Corral-De la Calle M, Arranz-Sánchez D, Gonzalez-Beato MJ, De Lucas R, Vidaurrázaga C. Tongue ulcer in a child: Riga-Fede disease. J Eur Acad Dermatol Venereol. 2006;20(10):1357-1359. doi: 10.1111/j.1468-3083.2006.01715.x
7. Çavuş Ş, Özmen B. Riga-Fede disease in the upper jaw in an infant. Dermatol Ther. 2017;30(5): e12517. doi: 10.1111/dth.12517
8. Paranna S, Kamath P. Riga-Fede disease in association with natal teeth. J Dent Res Rev. 2017;4(4):69-71. Available from: https://www.jdrr.org/temp/JDentResRev4369-3141635_084336.pdf
9. Iandolo A, Amato A, Sangiovanni G, Argentino S, Pisano M. Riga-Fede disease: A systematic review and report of two cases. Eur J Paediatr Dent. 2021;22(4):323-331. doi: 10.23804/ejpd.2021.22.04.11
10. Alamankany A. Riga-Fede disease associated with Fabry's disease and Niemann-Pick C disease in a boy with microcephaly: A case report. Int J Health Sci (Qassim). 2021;15(1):56-58. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786439/
11. Baghdadi ZD: Riga-Fede disease: association with microcephaly. Int J Paediatr Dent. 2002; 12(6):442–445. doi: 10.1046/j.1365-263X.2002.00396.x
12. Domingues CJ, Herrera A, Fernandez CP, Garcia BB, Camacho F: Riga-Fede disease associated with postanoxic encephalopathy and trisomy 21: a proposed classification. PediatrDermatol. 2007;24(6):663-665. doi: 10.1111/j.1525-1470.2007.00564.x
13. Picciotti M, DiVece L, Viviano M, Giorgio A, Lorenzini G. Meningitis and Riga-Fede disease: an unusual condition. Eur J Paediatr Dent. 2014;15(2 Suppl):245-246. Available from: https://pubmed.ncbi.nlm.nih.gov/25101514/
14. Bhatt R, Dave B, Sheth M. Riga-Fede Disease: Report of a case with literature review. Adv Hum Biol. 2015;5(1):52-55. Available from: https://oaji.net/articles/2015/957-1433399456.pdf
15. Jamani NA, Ardini YD, Harun NA. Neonatal tooth with Riga-Fide disease affecting breastfeeding: a case report. Int Breastfeed J. 2018;13:35. doi: 10.1186/s13006-018-0176-7
16. Terzioğlu A, Bingül F, Aslan G. Lingual traumatic ulceration (Riga-Fede disease). J Oral Maxillofac Surg. 2002;60(4):478. doi: 10.1053/joms.2002.32070
17. Baghdadi ZD. Riga-Fede disease: report of a case and review. J Clin Pediatr Dent. 2001;25(3):209-213. doi: 10.17796/jcpd.25.3.9725k31q263800km
18. Deep SB, Ranadheer E, Rohan B. Riga-Fede disease: report of a case with literature review. J Advanced Oral Research. 2011;2(2):27-30. doi: 10.1177/2229411220110205
19. Lakshmanan S, Venkataraman S, Singh U. Riga-Fede disease: a mimicker of malignancy. MJ Case Rep. 2021;14(3):235976. doi: 10.1136/bcr-2020-235976
20. Padmanabhan MY, Pandey RK, Aparna R, Radhakrishnan V. Neonatal sublingual traumatic ulceration – case report & review of the literature. Dent Traumatol. 2010;26(6):490-495. doi: 10.1111/j.1600-9657.2010.00926.x
21. Kumari A, Singh PK. Diagnosis of Riga-Fede disease. Indian J Pediatr. 2019;86(2):191. doi: 10.1007/s12098-018-2776-z
22. Rao RS, Mathad SV. Natal teeth: case report and review of literature. J Oral Maxillofac Pathol. 2009;13(1):41-46. doi: 10.4103/0973-029X.44574
23. Samadi F, Babaji P, Saha S, Katiyar A, Chowdhry S. Natal teeth: report of two cases and review of literature. Int J Oral Maxillofac Pathol. 2011;2(1):33-36. Available from: https://www.researchgate.net/publication/255485983_Natal_Teeth_Report_of_Two_Cases_and_Review_of_Literature
24. Patil SD, Dixit U. A Trio discovery – Cardarelli-Riga-Fede disease: a case report and review of literature. J Contemp Dent. 2013;3(1):44-48. doi: 10.5005/jp-journals-10031-1034
25. Hegde RJ. Sublingual traumatic ulceration due to neonatal teeth (Riga-Fede disease). J Indian Soc Pedod Prev Dent. 2005;23(1):51-52. doi: 10.4103/0970-4388.16031
26. Hong P. Riga-Fede disease: traumatic lingual ulceration in an infant. J Pediatr. 2015;167(1):204. doi: 10.1016/j.jpeds.2015.03.034
27. Daraz D, Brij B, Shabir R, Afshan. Natal teeth, neonatal teeth and Riga-Fede syndrome: a case report. EJPMR. 2019;6(11):420-423. Available from: https://storage.googleapis.com/journal-uploads/ejpmr/article_issue/1588422257.pdf
28. Baroni A, Capristo C, Rossiello L, Faccenda F, Satriano RA. Lingual traumatic ulceration (Riga-Fede disease). Int J Dermatol. 2006;45(9):1096-1097 doi: 10.1111/j.1365-4632.2004.02554.x
29. Silva Díaz E, Estébanez Corrales A, Miralles Palmero A, Martín Hernández JM. Enfermedad de Riga-Fede [Riga-Fede disease]. An Pediatr (Engl Ed). 2018;89(6):389-390. doi: 10.1016/j.anpedi.2018.02.014
30. Lee J, Mandel L. Rigo-Fede disease: case report. N Y State Dent J. 2014;80(2):36-37. Available from: https://www.researchgate.net/publication/262581128_Rigo-Fede_disease_case_report
31. Eley KA, Watt-Smith PA, Watt-Smith SR: Deformity of the tongue in an infant: Riga-Fede disease. Paediatr Child Health. 2010;15(1):581-582. doi: 10.1093/pch/15.9.581
32. Sonali S, Samadi F, Saha S. Riga’s papilloma in a 3 month old infant: a case report. J Internat Dental Medical Res. 2011;4(1):12-16. Available from: http://www.jidmr.com/journal/DENTISTRY/2011/vol4_no1/3_D1083_Sonali_Saha.pdf
33. van der Meij EH, de Vries TW, Eggink HF, de Visscher JG. Traumatic lingual ulceration in a newborn: Riga-Fede disease. Ital J Pediatr. 2012;38:20. doi: 10.1186/1824-7288-38-20
34. Jingarwar MM, Bajwa NK, Pathak A. Riga Fede disease: Fibrous hyperplasia associated with natal teeth in an infant. A case report and clinical update. Indian J Neonatal Medicine Research. 2014;2(1):11-13. Available from: https://www.ijnmr.net/article_fulltext.asp?issn=0973-709x&year=2014&month=July&volume=2&issue=1&page=11&id=2004
35. Cunha RF, Boer FAC, Torriani DD, Frossard WTG. Natal and neonatal teeth: review of the literature. Pediat Dent. 2001;23(2):158-162. Available from: https://www.aapd.org/globalassets/media/publications/archives/cunha-23-02.pdf
36. Basavraju S, Verma KG, Singla M, Verma P. An Associated Polydactyly with Riga – Fede Disease: A Rare Case Report. J Oral Medicine, Oral Surg Oral Med Oral Pathol Oral Radiol. 2015;1(1):36-38. Available from: https://www.joooo.org/article-details/534
37. Eita AAB. Congenital anomalies-associated Riga-Fede disease as an early manifestation of Lesch-Nyhan syndrome: rare entities in the same pediatric patient-a case report. BMC Oral Health. 2022;22(1):26. doi: 10.1186/s12903-022-02060-1
38. Toy BR: Congenital autonomic dysfunction with universal pain loss (Riga-Fede disease). Dermatol Online J. 2001;7(2):17. doi: 10.5070/D35J62N3K3
39. Narang T, De D, Kanwar AJ: Riga-Fede disease: trauma due to teeth or tongue tie? J Eur Acad Dermatol Venereol. 2008,22(3):395–396. doi: 10.1111/j.1468-3083.2007.02347.x
40. Ozmen B, Acar O. Persistent untreated Riga-Fede disease for 6 years. Pediatr Dermatol. 2015;32(3):e134-135. doi: 10.1111/pde.12569
41. Li J, Zhang YY, Wang NN, Bhandari R, Liu QQ. Riga-Fede disease in a child. Clin Exp Dermatol. 2016;41(3):285-286. doi: 10.1111/ced.12728
42. Yürekli A, Dinçer D. Successfully Treated Riga-Fede Disease. Dermatol Pract Concept. 2019;9(3):218-219. doi: 10.5826/dpc.0903a11
43. Leung AKC, Robson WLM: Natal teeth: a review. J Natl Med Assoc. 2006, 98(2):226–228. Available from: https://www.researchgate.net/publication/299186430_Natal_teeth_A_review
44. Calistru AM, Lisboa C, Bettencourt H, Azevedo F. Case for diagnosis. Riga-Fede disease. An Bras Dermatol. 2012;87(5):791-792. doi: 10.1590/s0365-05962012000500025
45. Senanayake MP, Karunaratne I. Persistent lingual ulceration (Riga-Fede disease) in an infant with Down syndrome and natal teeth: a case report. J Med Case Rep. 2014;8:283. doi: 10.1186/1752-1947-8-283
46. Polat Ekinci A, Kılıç S, Babuna Kobaner G. Early-onset and persistent traumatic granuloma of the tongue (Riga-Fede disease) associated with neonatal teeth and Down syndrome. J Eur Acad Dermatol Venereol. 2019;33(3):131-132. doi: 10.1111/jdv.15336
47. Taghi A, Motamedi MH. Riga-Fede disease: a histological study and case report. Indian J Dent Res. 2009;20(2):227-229. doi: 10.4103/0970-9290.52893
48. Mhaske S, Yuwanati MB, Mhaske A, Ragavendra R, Kamath K, Saawarn S. Natal and neonatal teeth: an over-view of the literature. ISRN Pediatr. 2013;18;2013:956269. doi: 10.1155/2013/956269
49. Costacurta M, Maturo P, Docimo R. Riga-Fede disease and neonatal teeth. Oral Implantol (Rome). 2012;5(1):26-30. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533976/
50. Lee JJ, Sarangam M, Feldman KW, Tieder JS. Riga-Fede disease: a case of sublingual trauma not associated with abuse. Pediatr Emerg Care. 2021;37(12):e1735-e1737. doi: 10.1097/PEC.0000000000001922
51. Singh R, Lakhanam M. Riga-Fede disease associated with natal teeth in a premature female child: a case report. Asian Journal of Dental Sciences. 2021;11:69-76. doi: 10.9734/bpi/rdmmr/v11/2658E
52. Shakovets NV, Terekhova TN. Oral examination of infants and toddlers. Pediatric dentistry and dental prophylaxis. 2014;13(4):13-17. Available from: https://www.elibrary.ru/download/elibrary_22833364_97606027.pdf
53. Baldiwala M, Nayak R. Conservative Management of Riga-Fede disease. J Dent Child. 2014;81:103-106. Available from: https://pubmed.ncbi.nlm.nih.gov/25198954/
54. Alahmari A, Alahmari AS. Management of Riga-Fede disease: A case report. Dentistry. 2017;7(2):413. doi: 10.4172/2161-1122.1000413
55. Kanumuri PK. Riga Fede Disease. J Neonatal Surg. 2017;6(1):20. doi:10.21699/jns.v6i1.475
56. Marie J, Fricain JC, Boralevi F. Maladie de Riga-Fede [Riga-Fede disease]. Ann Dermatol Venereol. 2012;139(8-9):546-549. doi: 10.1016/j.annder.2012.05.001
57. Dunlop R, Barton D, Jones J. Riga-fede disease: a case report. J Pediatr Health Care. 2013;27(2):155-157. doi: 10.1016/j.pedhc.2012.07.019
58. Danelon M, Emerenciano NG. Garcia LG, Percinoto C, Cunha RF. Natal teeth associated with Riga-Fede ulcer: case report. Arch Health Investigation. 2017;6(4):177-180. doi: 10.21270/archi.v6i4.2059
59. Graillon N, Dumont N, Guyot L. Maladie de Riga-Fede: ulcération traumatique de la langue chez un nourrisson [Riga-Fede disease: traumatic ulceration of the tongue in an infant]. Rev Stomatol Chir Maxillofac Chir Orale. 2013;114(2):113-115. doi: 10.1016/j.revsto.2013.01.010
60. Da Silva, DC, Freitas PM, Calvo AF, Bissoto GiT, Zanola M, Imparato JC P. Treatment of Riga-Fede disease using laser therapy: clinical case report. Revista Gaúcha de Odontologia. 2017;65(1):87-91. doi: 10.1590/1981-86372017000100003323
61. Wang CH, Lin YT, Lin YJ. A survey of natal and neonatal teeth in newborn infants. J Formos Med Assoc. 2017;116(3):193-196. doi: 10.1016/j.jfma.2016.03.009
62. Kariya PB, Shah S, Singh S, Buch A. Riga-Fede disease associated with syndactyly and oligodactyly: A rare occurrence. J Clin Pediatr Dent. 2019;43(5):356-359. doi: 10.17796/1053-4625-43.5.10
63. Choi SC, Park JH, Choi YC, Kim GT. Sublingual traumatic ulceration (a Riga-Fede disease): report of two cases. Dent Traumatol. 2009;25(3):e48-e50. doi: 10.1111/j.1600-9657.2009.00773.x
64. Kana A, Markou L, Arhakis A, Kotsanos N. Natal and neonatal teeth: a systematic review of prevalence and management. Eur J Paediatr Dent. 2013;14(1):27-32. Available from: https://www.researchgate.net/publication/236226439_Natal_and_Neonatal_Teeth_A_Systematic_Review_of_Prevalence_and_Management
65. Nogueira I, Gonçalves F, Moda L, Oliveira R. Riga-Fede disease: double case-report – a conservative and other radical. Rev Assoc Paul Cir Dent. 2014;68(2):100-104. Available from: http://revodonto.bvsalud.org/pdf/apcd/v68n2/a03v68n2.pdf
66. Bafna Y, Khandelwal V, Bafna M, Nayak PA. Management of sublingual ulceration in a 12-month-old child. BMJ Case Rep. 2013;2013:bcr2013200356. doi: 10.1136/bcr-2013-200356
67. Nawaz M, Krishnamurthy S, Sivaraman GS, SivakumarS, Nawaz N. Riga Fede disease – A case report. JMSCR. 2016;4(6):11089-11091. doi: 10.18535/jmscr/v4i6.67
68. Volpato LE, Simões CA, Simões F, Nespolo PA, Borges ÁH. Riga-Fede disease associated with natal teeth: Two different approaches in the same case. Case Rep Dent. 2015;2015:234961. doi: 10.1155/2015/234961
Review
For citations:
Fomenko I.V., Maslak E.E., Kasatkina A.L., Bavlakova V.V., Fursik D.I. Riga-Fede disease: a review of the literature and a description of clinical cases. Pediatric dentistry and dental prophylaxis. 2023;23(2):160-167. (In Russ.) https://doi.org/10.33925/1683-3031-2023-614
Views:
785
Email this article 
