Characteristics of the microflora of the mouth cavity belonged to the children suffering from chronic recurrent aphthous stomatitis

Abstract

Significant role in the pathogenesis of chronic recurrent aphthous stomatitis is attributed to the infectious-allergic factor, changes in the immune system of the body. With a decrease in general and, especially, local immunity of the mouth cavity, the species composition of the microflora changes, its aggressiveness and antibiotic resistance increase. The aim of the study was to study the qualitative and quantitative structure of microbiocenosis of mouthy cavity belonged to the children with chronic recurrent aphthous stomatitis. 30 children suffering from chronic recurrent aphthous stomatitis (group 1) aged from 4 to 15 years took part in this research. 20 almost healthy children (group 2) at the age from 4 to 15 years without chronic recurrent aphthous stomatitis and concomitant somatic pathology have been formed as a control group. As a result of the study, all patients suffering from chronic recurrent aphthous stomatitis were diagnosed with microbiocenosis disorder of the mouth cavity. In 100% of cases, a high sensitivity to bacteriophages was revealed what makes it possible in some cases to exclude the use of antibiotics and to provide treatment with bacteriophages.