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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">detstom</journal-id><journal-title-group><journal-title xml:lang="ru">Стоматология детского возраста и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric dentistry and dental prophylaxis</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3031</issn><issn pub-type="epub">1726-7218</issn><publisher><publisher-name>RPA</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33925/1683-3031-2025-922</article-id><article-id custom-type="elpub" pub-id-type="custom">detstom-922</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLE</subject></subj-group></article-categories><title-group><article-title>Некоторые витамины и минералы в сыворотке крови и волосах у детей с разным уровнем минерализации эмали зубов</article-title><trans-title-group xml:lang="en"><trans-title>Serum and hair levels of selected vitamins and minerals in children with varying enamel mineralization levels</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8471-6193</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лимина</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Limina</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лимина Алиса Петровна, ассистент кафедры детской и терапевтической стоматологии имени Ю. А. Федорова</p><p>191015, ул. Кирочная, д. 41, г. Санкт-Петербург </p></bio><bio xml:lang="en"><p>Alisa P. Limina, DMD, Assistant Professor, Department of the Pediatric Dentistry</p><p>41 Kirochnaya Str., Saint Petersburg, 191015 </p></bio><email xlink:type="simple">alisa.limina@szgmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9801-503X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сатыго</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Satygo</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сатыго Елена Александровна, доктор медицинских наук, профессор, заведующая кафедрой детской и терапевтической стоматологии имени Ю. А. Федорова</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Elena A. Satygo, DMD, PhD, DSc, Professor, Head of the Department of Pediatric Dentistry</p><p>Saint Petersburg</p></bio><email xlink:type="simple">stom9@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Северо-Западный государственный медицинский университет имени И. И. Мечникова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-Western State Medical University named after I. I. Mechnikov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>01</day><month>08</month><year>2025</year></pub-date><volume>25</volume><issue>2</issue><fpage>187</fpage><lpage>195</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лимина А.П., Сатыго Е.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Лимина А.П., Сатыго Е.А.</copyright-holder><copyright-holder xml:lang="en">Limina A.P., Satygo E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.detstom.ru/jour/article/view/922">https://www.detstom.ru/jour/article/view/922</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Кариес имеет высокую распространенность и интенсивность у детей в период сменного прикуса. На развитие кариозного процесса влияют местные и общие факторы. Местные факторы развития кариеса у детей довольно хорошо изучены. Тем не менее общее состояние организма также влияет на интенсивность кариозных поражений. Витамины оказывают большое влияние на обменные процессы в организме ребенка и занимают важное место в клинической практике врача, в том числе детского стоматолога. Цель. Изучить роль некоторых витаминов и минералов в сыворотке крови и волосах у детей с низким уровнем минерализации эмали в профилактике кариеса зубов.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследовании приняли участие 143 человека, с 6 до 12 лет, средний возраст ≈8,7 ± 1,3 лет. При осмотре определялись следующие параметры: интенсивность кариеса (индекс КПУ), прирост интенсивности кариеса. По назначению педиатра пациентам проводился сбор крови и волос в клинической лаборатории, назначался прием витаминных, витаминно-минеральных комплексов.</p></sec><sec><title>Результаты</title><p>Результаты. Нами установлено, что у пациентов, которые в течение трех месяцев принимали по назначению педиатра витаминный комплекс в возрастной дозировке, через год наблюдений индекс КПУ увеличился с 2,31 ± 0,07 до 3,43 ± 0,05, прирост интенсивности кариеса составил 1,12 ± 0,02. У пациентов, в течение трех месяцев принимавших по назначению педиатра витаминно-минеральный комплекс в возрастной дозировке, через год наблюдений прирост интенсивности кариеса составил 0,60 ± 0,78, с 2,10 ± 0,02 до 2,70 ± 0,80. Индекс КПУ у пациентов, в течение трех месяцев ежедневно принимавших по назначению педиатра препарат Mg+B6 в возрастной дозировке, через год наблюдений достоверно повысился с 2,25 ± 0,02 до 2,31 ± 0,78, прирост интенсивности составил 0,85 ± 0,60. У пациентов контрольной подгруппы прирост интенсивности был 2,13 ± 0,03, так как КПУ увеличился с 2,25 ± 0,02 до 4,23 ± 0,05.</p></sec><sec><title>Заключение</title><p>Заключение. Комплексное применение витаминов и микроэлементов положительно влияет на прирост интенсивности кариеса у детей с низким уровнем минерализации эмали.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. Dental caries remains highly prevalent and severe in children during the mixed dentition period. Its development is influenced by both local and systemic factors. Although local aetiological factors of caries in children are relatively well understood, systemic health remains an important determinant of caries severity. Vitamins substantially impact metabolic processes in children and are essential in clinical practice, including pediatric dentistry. Objective. To investigate the role of selected vitamins and minerals, as measured in serum and hair, in preventing dental caries in children with low enamel mineralization.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The study included 143 children aged 6 to 12 years (mean age ≈ 8.7 ± 1.3 years). Clinical examination involved the assessment of caries severity using the DMFT index and evaluation of caries increment. As prescribed by a pediatrician, blood and hair samples were collected in a clinical laboratory, and vitamin or vitamin–mineral supplements were administered accordingly.</p></sec><sec><title>Results</title><p>Results. Among children who received an age-appropriate vitamin complex for three months, the DMFT index increased from 2.31 ± 0.07 to 3.43 ± 0.05 over the one-year observation period, corresponding to a caries increment of 1.12 ± 0.02. In those who received a combined vitamin–mineral supplement, the DMFT index rose from 2.10 ± 0.02 to 2.70 ± 0.80, with a lower caries increment of 0.60 ± 0.78. Among children administered an Mg + B6 supplement daily for three months, the index changed from 2.25 ± 0.02 to 2.31 ± 0.78, resulting in a caries increment of 0.85 ± 0.60. In contrast, the control subgroup showed the highest increase, with the DMFT index rising from 2.25 ± 0.02 to 4.23 ± 0.05 and a caries increment of 2.13 ± 0.03.</p></sec><sec><title>Conclusion</title><p>Conclusion. Combined supplementation with vitamins and minerals was also associated with a more favorable caries increment in this group.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>витамины</kwd><kwd>кариес</kwd><kwd>микроэлементы</kwd><kwd>минерализация</kwd><kwd>эмаль</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vitamins</kwd><kwd>dental caries</kwd><kwd>minerals</kwd><kwd>mineralization</kwd><kwd>enamel</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Скрипкина ГИ, Екимов ЕВ, Митяева ТС. Минерализующий потенциал ротовой жидкости в детском возрасте. Стоматология детского возраста и профилактика. 2019;19(3):47-51. doi: 10.33925/1683-3031-2019-19-3-47-51</mixed-citation><mixed-citation xml:lang="en">Skripkina GI, Ekimov EV, Mityaeva TS. Mineralizing potential of oral fluid in childhood. 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