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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">detstom</journal-id><journal-title-group><journal-title xml:lang="ru">Стоматология детского возраста и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric dentistry and dental prophylaxis</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3031</issn><issn pub-type="epub">1726-7218</issn><publisher><publisher-name>RPA</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33925/1683-3031-2024-840</article-id><article-id custom-type="elpub" pub-id-type="custom">detstom-840</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLE</subject></subj-group></article-categories><title-group><article-title>Возможности безопасного использования фторсодержащих зубных паст для профилактики кариеса зубов у детей</article-title><trans-title-group xml:lang="en"><trans-title>Safe use of fluoride-containing toothpastes for caries prevention in children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8160-6965</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хамадеева</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Khamadeeva</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хамадеева Альфия Минвалиевна, доктор медицинских наук, профессор, профессор кафедры стоматологии детского возраста и ортодонтии</p><p>Самара  </p></bio><bio xml:lang="en"><p>Alfiia M. Khamadeeva, DMD, PhD, DSc, Professor, Department of the Pediatric Dentistry and Orthodontics</p><p>Samara </p></bio><email xlink:type="simple">ca.51@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4454-984X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попов</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Popov</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Попов Николай Владимирович, доктор медицинских наук, доцент, директор Стоматологического института, заведующий кафедрой стоматологии детского возраста и ортодонтии</p><p>Самара </p></bio><bio xml:lang="en"><p>Nicolai V. Popov, DMD, PhD, Docent, Professor, Department of the Pediatric Dentistry and Orthodontic</p><p>Samara </p></bio><email xlink:type="simple">studmfc@samsmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8532-288X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баймуратова</surname><given-names>Л. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Baimuratova</surname><given-names>L. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Баймуратова Лилия Рамилевна, аспирант кафедры стоматологии детского возраста и ортодонтии</p><p>443099, ул. Чапаевская, д. 89, г. Самара</p></bio><bio xml:lang="en"><p>Liliya R. Baimuratova, DMD, PhD student, Department of the Pediatric Dentistry and Orthodontics</p><p>89 Chapaevskaya Str., Samara, 443099</p></bio><email xlink:type="simple">LiliyaBaimuratova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6917-2586</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козупица</surname><given-names>Г. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozupitsa</surname><given-names>G. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Козупица Геннадий Степанович, доктор биологических наук, профессор кафедры физического образования и спорта</p><p>Самара </p></bio><bio xml:lang="en"><p>Gennady S. Kozupitsa, PhD, DSc, Professor, Department of the Physical Education and Sports</p><p>Samara </p></bio><email xlink:type="simple">rektorat@samgups.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6207-5575</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петрухина</surname><given-names>И. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrukhina</surname><given-names>I. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петрухина Ирина Константиновна, доктор фармакологических наук, доцент, заместитель директора Института фармации, заведующий кафедрой управления и экономики фармации – базовой кафедры «Аптеки Плюс»</p><p>Самара </p></bio><bio xml:lang="en"><p>Irina K. Petrukhina, PhD, DSc, Docent, Director of the Institute of Pharmacy, Head of the Department of Management and Economics of Pharmacy – Basic Department of Apteki Plus</p><p>Samara </p></bio><email xlink:type="simple">i.k.petrukhina@samsmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4287-8386</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сазанова</surname><given-names>К. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sazanova</surname><given-names>K. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сазанова Ксения Николаевна, кандидат фармакологических наук, старший преподаватель кафедры управления и экономики фармации – базовой кафедры «Аптеки Плюс»</p><p>Самара </p></bio><bio xml:lang="en"><p>Ksenia N. Sazanova, PhD, Senior Lecture, Department of the Management and Economics of Pharmacy – Basic Department of Apteki Plus</p><p>Samara </p></bio><email xlink:type="simple">k.n.sazanova@samsmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8109-8713</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ногина</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nogina</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ногина Наталья Вячеславовна, кандидат медицинских наук, доцент кафедры стоматологии ИПО</p><p>Самара </p></bio><bio xml:lang="en"><p>Natalya V. Nogina, PhD, Associate Professor, Department of the Dentistry IPO</p><p>Samara </p></bio><email xlink:type="simple">noginanatalya@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-0554-4348</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Марьсюкаева</surname><given-names>Д. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Marsykaeva</surname><given-names>D. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Марьсюкаева Динара Ринатовна, практический медицинский психолог</p><p>Самара </p></bio><bio xml:lang="en"><p>Dinara R. Marsykaeva, Medical Psychologist</p><p>Samara </p></bio><email xlink:type="simple">marsukaeva163@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Самарский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Самарский государственный университет путей сообщения</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State University of Railway Transport</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Самарская областная детская клиническая больница имени Н.Н. Ивановой</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara Regional Children's Clinical Hospital named after N.N. Ivanova</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>28</day><month>01</month><year>2025</year></pub-date><volume>24</volume><issue>4</issue><fpage>358</fpage><lpage>367</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Хамадеева А.М., Попов Н.В., Баймуратова Л.Р., Козупица Г.С., Петрухина И.К., Сазанова К.Н., Ногина Н.В., Марьсюкаева Д.Р., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Хамадеева А.М., Попов Н.В., Баймуратова Л.Р., Козупица Г.С., Петрухина И.К., Сазанова К.Н., Ногина Н.В., Марьсюкаева Д.Р.</copyright-holder><copyright-holder xml:lang="en">Khamadeeva A.M., Popov N.V., Baimuratova L.R., Kozupitsa G.S., Petrukhina I.K., Sazanova K.N., Nogina N.V., Marsykaeva D.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.detstom.ru/jour/article/view/840">https://www.detstom.ru/jour/article/view/840</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. В Чапаевске Самарской области после мероприятий по экологической реабилитации отмечена тенденция роста распространенности и интенсивности кариеса зубов, особенно у детей дошкольного возраста.</p></sec><sec><title>Цель</title><p>Цель: обоснование безопасности использования фторидов для профилактики кариеса зубов у детей.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Проведено анкетирование 124 родителей детей 5-6 лет, посещающих дошкольные детские образовательные организации и 361 подростка 12 и 15 лет по вопроснику ВОЗ (2013). Проанализированы ответы о гигиенических привычках по уходу за ртом. Концентрации фтор-иона в питьевой воде определялись потенциометрическим методом по ГОСТ 4386-89 С.6, в моче – по ГОСТ 8.563-96, в зубных пастах по ГОСТ 7983-2016. Определен рейтинг фторсодержащих паст в аптечной сети и супермаркетах. Статистический анализ проводился с использованием программы IBM SPSS Statistics v.26 (разработчик – IBM Corporation).</p></sec><sec><title>Результаты</title><p>Результаты. Содержание фторидов в питьевой воде снизилось с 0,78-0,91 до 0,49-0,71 мг/л за последние 15 лет после мероприятий по экологической реабилитации в городе, но остались на субоптимальном уровне для профилактики кариеса зубов. Анализ фракции фторидов, экскретированной почками, свидетельствует о низком суммарном поступлении фторидов из воды, зубных паст, пищи. Выявлена слабая корреляционная связь между кпу зубов с уровнем фтора в моче (ρ = 0,35) и эмпирическим уровнем фтора в организме (ρ = 0,36). Эти данные свидетельствуют о низком уровне поступления фторидов в организм, что абсолютно исключает токсическое влияние на здоровье. Проведенный анализ выбора зубных паст свидетельствует о предпочтительном выборе населением паст без фтора или с его содержанием ниже 1000 ppm. Этому способствует ассортимент в торговле, настороженность в их использовании, которая сформировалась в условиях низкой приверженности у населения к профилактике стоматологических заболеваний и под влиянием дезинформации о значении фтора для профилактики кариеса зубов на интернет-ресурсах. Настоящее исследование доказало, что фактическое содержание фтор-иона в 22 наиболее популярных среди населения зубных пастах не выходит за пределы технологически приемлемых границ.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. Following environmental rehabilitation efforts in Chapayevsk, Samara Region, an increase in the prevalence and severity of dental caries has been observed, particularly among preschool-aged children.</p></sec><sec><title>Objective</title><p>Objective. To evaluate the safety of fluoride use for preventing dental caries in children.</p></sec><sec><title>Material and methods</title><p>Material and methods. A survey was conducted among 124 parents of children aged 5–6 years attending preschools and 361 adolescents aged 12 and 15 years, using the WHO questionnaire (2013). Responses regarding oral hygiene habits were analyzed. Fluoride ion concentrations were measured in drinking water using the potentiometric method (GOST 4386-89 S.6), in urine according to GOST 8.563-96, and in toothpastes following GOST 7983-2016. The availability and popularity of fluoride-containing toothpastes in pharmacies and supermarkets were also assessed. Statistical analysis was performed using IBM SPSS Statistics v.26 (IBM Corporation).</p></sec><sec><title>Results</title><p>Results. Over the past 15 years, the fluoride content in drinking water decreased from 0.78–0.91 mg/L to 0.49– 0.71 mg/L following the city’s environmental rehabilitation efforts, remaining suboptimal for caries prevention. Analysis of fluoride excretion via the kidneys indicated low overall fluoride intake from water, toothpaste, and food. A weak correlation was found between the DMFT (decayed, missing, and filled teeth) index and urinary fluoride levels (ρ = 0.35), as well as estimated systemic fluoride levels (ρ = 0.36). These results indicate low fluoride intake, eliminating concerns about toxic effects on health. An analysis of toothpaste preferences showed that the population primarily chooses fluoride-free toothpastes or those with fluoride levels below 1000 ppm. This trend is influenced by the product range available, low adherence to preventive dental care, and misinformation from online sources that often attribute negative effects to fluoridation or raise safety concerns. The actual fluoride content in toothpastes was found to be within acceptable technological limits.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>кариес</kwd><kwd>дети</kwd><kwd>фтор в воде</kwd><kwd>почечная экскреция фторидов с мочой</kwd><kwd>фтор в зубных пастах</kwd></kwd-group><kwd-group xml:lang="en"><kwd>caries</kwd><kwd>children</kwd><kwd>fluoride in water</kwd><kwd>renal fluoride excretion</kwd><kwd>fluoride in toothpastes</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">World Dental Federation FDI. Promoting oral health through fluoride: Adopted by the FDI General Assembly: August 2017, Madrid, Spain. Int Dent J. 2018;68(1):16-17. doi: 10.1111/idj.12372.</mixed-citation><mixed-citation xml:lang="en">World Dental Federation FDI. Promoting oral health through fluoride: Adopted by the FDI General Assembly: August 2017, Madrid, Spain. 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