<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">detstom</journal-id><journal-title-group><journal-title xml:lang="ru">Стоматология детского возраста и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Pediatric dentistry and dental prophylaxis</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3031</issn><issn pub-type="epub">1726-7218</issn><publisher><publisher-name>RPA</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33925/1683-3031-2024-806</article-id><article-id custom-type="elpub" pub-id-type="custom">detstom-806</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ  СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORT</subject></subj-group></article-categories><title-group><article-title>Опыт применения препаратов «Этоксисклерол» и «Блеомицин» при лечении детей с ретенционными кистами слюнных желез: клинические случаи</article-title><trans-title-group xml:lang="en"><trans-title>Clinical application of "Ethoxysclerol" and "Bleomycin" in the management of retention cysts of the salivary glands in pediatric patients: case studies</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5740-2287</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бакши</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bakshi</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бакши Татьяна Андреевна, аспирант кафедры детской челюстно-лицевой хирургии</p><p>Москва</p></bio><bio xml:lang="en"><p>Tatiana A. Bakshi, DDS, PhD-student, Department of the Pediatric Maxillofacial Surgery</p><p>Moscow</p></bio><email xlink:type="simple">tatianabakshi@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2501-8552</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлев</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakovlev</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Яковлев Сергей Васильевич, кандидат медицинских наук, доцент кафедры детской челюстно-лицевой хирургии</p><p>Москва</p></bio><bio xml:lang="en"><p>Sergey V. Yakovlev, DDS, PhD, Associate Professor, Department of the Pediatric Maxillofacial Surgery</p><p>Moscow</p></bio><email xlink:type="simple">serg.yak@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3896-3756</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Топольницкий</surname><given-names>О. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Topolnitskiy</surname><given-names>O. Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Топольницкий Орест Зиновьевич, доктор медицинских наук, профессор, заведующий кафедрой детской челюстно-лицевой хирургии</p><p>Москва</p></bio><bio xml:lang="en"><p>Orest Z. Topolnitsky, DDS, PhD, DSc, Professor, Head of the Department of Pediatric Maxillofacial Surgery</p><p>Moscow</p></bio><email xlink:type="simple">proftopol@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7296-5800</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гургенадзе</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Gurgenadze</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гургенадзе Анна Панаетовна, кандидат медицинских наук, доцент, заведующий учебной частью детской челюстно-лицевой хирургии</p><p>Москва</p></bio><bio xml:lang="en"><p>Anna P. Gurgenadze, DDS, PhD, Department of the Pediatric Maxillofacial Surgery</p><p>Moscow</p></bio><email xlink:type="simple">dethirstom@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский университет медицины</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian University of Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>19</day><month>07</month><year>2024</year></pub-date><volume>24</volume><issue>2</issue><fpage>197</fpage><lpage>201</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бакши Т.А., Яковлев С.В., Топольницкий О.З., Гургенадзе А.П., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Бакши Т.А., Яковлев С.В., Топольницкий О.З., Гургенадзе А.П.</copyright-holder><copyright-holder xml:lang="en">Bakshi T.A., Yakovlev S.V., Topolnitskiy O.Z., Gurgenadze A.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.detstom.ru/jour/article/view/806">https://www.detstom.ru/jour/article/view/806</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Одним из частых заболеваний, встречающихся в практике стоматолога, является ретенционная киста слюнной железы. Традиционным методом лечения считается цистаденэктомия и цистотомия образования. При этом после операции встречаются такие осложнения как рецидив, травма соседних структур (протоков соседних слюнных желез, сосудов и нервов), вскрытие капсулы поднижнечелюстной слюнной железы.</p><p>Описание клинических случаев. В статье показаны клинические случаи четырех пациентов, которые наблюдались на кафедре детской челюстно-лицевой хирургии Российского университета медицины с диагнозом «ретенционная киста слюнной железы». Всем пациентам было проведено лечение с использованием препаратов «Лауромакрогол-400» («Этоксисклерол») и «Блеомицин». В послеоперационном периоде не наблюдалось осложнений или побочных действий препаратов. На контрольных осмотрах клинических проявлений ретенционной кисты или признаков кисты на УЗИ не наблюдалось.</p></sec><sec><title>Заключение</title><p>Заключение. Склерозирование ретенционных кист слюнных желез может являться альтернативным малоинвазивным способом лечения, который позволяет избежать травматического хирургического лечения.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. Retention cysts of the salivary glands are a frequent occurrence in dental practice. Traditional treatments, such as cystadenectomy and cystotomy, are commonly employed. However, these procedures are associated with postoperative complications, including recurrence, damage to adjacent structures (e.g., ducts of neighbouring salivary glands, blood vessels, and nerves), and inadvertent opening of the submandibular salivary gland capsule.</p><p>Description of clinical cases. This paper presents clinical cases of four pediatric patients diagnosed with retention cysts of the salivary glands, treated at the Department of Pediatric Maxillofacial Surgery, Russian University of Medicine. All patients received treatment with "Lauromacrogol-400" ("Ethoxysclerol") and "Bleomycin." In the postoperative period, no complications or adverse effects related to the administered drugs were observed. Follow-up examinations revealed no clinical manifestations of retention cysts or ultrasonographic evidence of cysts.</p></sec><sec><title>Conclusions</title><p>Conclusions. Sclerotherapy using "Ethoxysclerol" and "Bleomycin" for the treatment of retention cysts of the salivary glands presents a viable minimally invasive alternative to conventional surgical methods, potentially mitigating the risks associated with more invasive procedures.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>ретенционная киста</kwd><kwd>слюнные железы</kwd><kwd>склерозирующая терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>retention cysts</kwd><kwd>salivary glands</kwd><kwd>sclerotherapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">More CB, Bhavsar K, Varma S, Tailor M. Oral mucocele: A clinical and histopathological study. J Oral Maxillofac Pathol. 2014;18(Suppl 1):S72-7. doi: 10.4103/0973-029X.141370.</mixed-citation><mixed-citation xml:lang="en">More CB, Bhavsar K, Varma S, Tailor M. Oral mucocele: A clinical and histopathological study. J Oral Maxillofac Pathol. 2014;18(Suppl 1):S72-7. doi: 10.4103/0973-029X.141370.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Kalra V, Mirza K, Malhotra A. Plunging ranula. J Radiol Case Rep. 2011;5(6):18-24. doi: 10.3941/jrcr.v5i6.682.</mixed-citation><mixed-citation xml:lang="en">Kalra V, Mirza K, Malhotra A. Plunging ranula. J Radiol Case Rep. 2011;5(6):18-24. doi: 10.3941/jrcr.v5i6.682.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Albsoul NM, Obeidat FO, Altaher RN, Jubouri SA, Hadidy AM. Recurrent right sublingual ranula, concomitant with ipsilateral submandibular salivary gland aplasia. Int J Surg Case Rep. 2013;4(2):229-31. doi: 10.1016/j.ijscr.2012.10.021.</mixed-citation><mixed-citation xml:lang="en">Albsoul NM, Obeidat FO, Altaher RN, Jubouri SA, Hadidy AM. Recurrent right sublingual ranula, concomitant with ipsilateral submandibular salivary gland aplasia. Int J Surg Case Rep. 2013;4(2):229-31. doi: 10.1016/j.ijscr.2012.10.021.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Talmor G, Nguyen B, Mir G, Badash I, Kaye R, Caloway C. Sclerotherapy for Benign Cystic Lesions of the Head and Neck: Systematic Review of 474 Cases. Otolaryngol Head Neck Surg. 2021;165(6):775-783. doi: 10.1177/01945998211000448</mixed-citation><mixed-citation xml:lang="en">Talmor G, Nguyen B, Mir G, Badash I, Kaye R, Caloway C. Sclerotherapy for Benign Cystic Lesions of the Head and Neck: Systematic Review of 474 Cases. Otolaryngol Head Neck Surg. 2021;165(6):775-783. doi: 10.1177/01945998211000448</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Liu JL, Zhang AQ, Jiang LC, Li KY, Liu FZ, Yuan DY, et al. The efficacy of polidocanol sclerotherapy in mucocele of the minor salivary gland. J Oral Pathol Med. 2018;47(9):895-899. doi: 10.1111/jop.12764</mixed-citation><mixed-citation xml:lang="en">Liu JL, Zhang AQ, Jiang LC, Li KY, Liu FZ, Yuan DY, et al. The efficacy of polidocanol sclerotherapy in mucocele of the minor salivary gland. J Oral Pathol Med. 2018;47(9):895-899. doi: 10.1111/jop.12764</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
